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Uncover the key genes behind your plant traits

Plant trait genomics: discover,
rank, and design candidate genes

From scientific literature to candidate genes and gene discovery — an integrated pipeline for plant biologists, genomic selection programs, and molecular breeders.

Integrated Trait Design Pipeline

A linear, AI-assisted workflow that takes you from a trait or biological process all the way to a ranked list of candidate genes in your organism of interest.

Text Mining
Orthology
GRN
Candidate Genes
Text Mining

Text Mining — Mining scientific literature

Automatically mines thousands of PubMed articles to uncover genes linked to your trait or biological process of interest. GREGOR brings together evidence from the published literature in one place.

Orthology

Orthology — From literature to your organism

Genes found in literature often come from model species like Arabidopsis. GREGOR maps them directly to your target organism's genome via NCBI RefSeq orthology — so you work with the exact genes in your species of interest, not just surrogates.

Gene Regulatory Network

GRN — The regulatory network of your trait

Goes beyond individual genes. Using the candidate genes from the orthology step, GREGOR constructs the Gene Regulatory Network (GRN) of your trait, revealing functional interactions and regulatory relationships between genes. Genes with lower network centrality and connectivity often represent the most promising intervention targets, as they tend to have more specific effects and lower pleiotropy risk.

Candidate Genes

Candidate Genes — Ranked and ready to act

A prioritized list of candidate genes ranked by integrated evidence from literature mining, orthology mapping, network centrality, and tissue-specific expression patterns. Results are designed for collaborative review, enabling multi-user annotation, validation, and selection — facilitating team-based gene discovery and streamlined editing target prioritization.

Gene Selection for Trait Editing

Select high-confidence candidate genes associated with a specific trait in your plant of interest. Prioritize editing targets backed by literature evidence, orthology, and network connectivity.

Gene Discovery

Explore genes associated with a biological process or set of terms — even without a predefined editing goal. Ideal for understanding trait architecture, identifying key regulators, and generating new hypotheses.

Collaboration & Sharing Share trait designs with other users for collaborative review and annotation. Export results and discuss them across your lab or institution.
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Supported organisms Currently available for Arabidopsis thaliana, Tomato, Raspberry, and Orange.
Arabidopsis Tomato Raspberry Orange
Need support for another organism? Contact us to request additional species coverage.

More Tools

Expand your genomic workflow with additional resources, from gene exploration to CRISPR target design.

Explore Genes

Explore Genes

Search across multiple plant genomes by gene name, annotation, organism, or sequence. Quickly access gene structure, expression profiles, orthologs, and key genomic insights.

Explore
CRISPR Design

CRISPR Design

Design sgRNAs for precise gene editing workflows. Find your gene of interest and launch CRISPR design tools directly from the gene information panel.

Design

Explore Genomes

Coming Soon

Browse supported plant genomes with genome-wide metrics, gene counts, structural annotations, and key statistics—all in one place.

Ready to discover your candidate genes?

Join researchers using GREGOR to accelerate plant trait genomics and candidate gene discovery.

Get in Touch

Questions about GREGOR, access requests, or organism support? We’d be glad to hear from you.

Contact

EMAIL

gregor@meristem.bio

WEBSITE

meristem.bio

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About GREGOR →